Expression Technologies Inc.

Other Chaperones

Molecular chaperones are important in cellular protein production. Some chaperones are involved in protein folding. Others are required for protein secretion. Still others are needed for disulfide bond formation. Absent or insufficient chaperones result in non-insoluble, unstable, or dysfunctional recombinant proteins. Chaperones are critical for the function of many proteins.

We engineered cell strains over express one or more molecular chaperones. Some of these chaperones are important for protein folding such as GroE and dnaKJ. Others are involved in peptidyl-prolyl-cis-trans-isomerization like trigger factor, PI and PPI. Dsb A, B, and C are critical for disulfide bond formation. skp promotes protein secretion.

Other factors also affect protein solubility, stability, and activity. Please click on respective word for more information.

Other chaperone strains:

Strain Name	Cat#	Gene	Description	Price (US$)
PlusEa^TM	10310	GroE	GroE contains GroES+EL E.coli chaperones	350
PlusKJa^TM	10320	dnaKJ	dna KJ contains dnaK+J E.coli chaperones	350
PlusDAa^TM	10330	Dsb A	Dsb A promotes disulfide bond formation	350
PlusDBa^TM	10340	Dsb B	Dsb B promotes disulfide bond formation	350
PlusDCa^TM	10350	Dsb C	Dsb C promotes disulfide fond formation	350
PlusTa^TM	10360	Trx	Thioredoxin increases solubility of proteins	350
PlusSa^TM	10370	skp	skp promotes protein secretion	350
PlusTFa^TM	10380	trigger factor	involves in protein folding, solubility and stability	350
PlusPIa^TM	10390	PI	peptidyl-prolyl-cis-trans-isomerase (PI)	350
PlusPPIa^TM	10400	PPI	periplasmic peptidyl-prolyl-cis-trans-isomerase (PPI)	350
PlusXLa^TM	10410	RXR LBD	Human retinoid X receptor β ligand binding domain	350
PlusEb^TM	10311	GroE	GroE contains GroES+EL E.coli chaperones	350
PlusKJb^TM	10321	dnaKJ	dna KJ contains dnaK+J E.coli chaperones	350
PlusDAb^TM	10331	Dsb A	Dsb A promotes disulfide bond formation	350
PlusDBb^TM	10341	Dsb B	Dsb B promotes disulfide bond formation	350
PlusDCb^TM	10351	Dsb C	Dsb C promotes disulfide fond formation	350
PlusTb^TM	10361	Trx	Thioredoxin increases solubility of proteins	350
PlusSb^TM	10371	skp	skp promotes protein secretion	350
PlusTFb^TM	10381	trigger factor	involves in protein folding, solubility and stability	350
PlusPIb^TM	10391	PI	peptidyl-prolyl-cis-trans-isomerase (PI)	350
PlusPPIb^TM	10401	PPI	periplasmic peptidyl-prolyl-cis-trans-isomerase (PPI)	350
PlusXLb^TM	10411	RXR LBD	Human retinoid X receptor β ligand binding domain	350

All the strain names ending with "a" are used in the expression with E.coli RNA polymerase and strain names ending with "b" are used in the expression with T7 RNA polymerase. The expression level of the specified gene in the two strains are comparable. All of the cell strains with ^TM superscripts are trademarks of Expression Technologies Inc. They are all patent-pending. These cell strains are for non-commercial research use only and they cannot be distributed out of the purchasing lab. Please contact us for any other uses.

Warranty

These cell strains are guaranteed to express the specified genes. In the case that the cell has an endogenous gene, the specified gene is overexpressed at least three times more than the endogenous expression level. Please email us at info@exptec.com for more information.